BIOLAN HEALTHTECHNOLOGY
The PoC solutions developed, produced and marketed by BIOLAN HEALTH are based on two technologies that have proven to be highly effective for the simple, rapid, non-invasive and cost-effective detection of a large number of parameters of interest in the medical sector.
These technologies are:
• Enzymatic biosensors based on electrochemical detection and screen-printing technology.
• Lateral flow immunoassays.
• Enzymatic biosensors based on electrochemical detection and screen-printing technology.
• Lateral flow immunoassays.
Enzymatic biosensors based on electrochemical detection and screen-printing technology:
They are presented as a powerful tool for the development of PoC devices, as they combine the high specificity of enzymes, with the advantages of electrochemical methods, including easy handling, sensitivity and compatibility with screen-printing, which allows the low-cost mass production of miniaturised devices. This has led to a steady growth in recent years in the development of enzymatic biosensors for application in the detection of a wide variety of analytes.
The operation of these biosensors is based on the immobilisation of an enzyme (chosen so that the substrate of this enzyme is the analyte to be determined) on the electrochemical transducer, which, after being exposed to a sample containing the target analyte, will transform the biological recognition process (which occurs between the enzyme and the analyte) into a quantifiable response (such as a current) that will allow us to determine the presence of the analyte in the sample analysed.
Lateral flow immunoassays:
Lateral flow (LF) immunoassays, such as the world-renowned pregnancy test, have dominated the rapid diagnostic market. These devices, based on the use of nitrocellulose membranes to support immunological reactions, are portable, fast and easy to use, allowing for Point of Care, PoC testing.
The operation of this type of FL immunosensors is based on the migration of a sample through a porous paper substrate, on which the immunological reactions take place. If the analyte is present in the sample, it can be detected visually by the appearance of a coloured band. This visual evaluation allows a qualitative analysis, but could be analysed quantitatively by means of a portable FL strip reader.
Ongoing projects
BIOLAN HEALTH is committed to collaborative projects as a way to increase its knowledge and technical skills.
Research and development framework Km0 to enable and accelerate the development and life cycle management of embedded medical devices that guarantee functional safety.
Acronym: OSASUNK0
Financing Program: HAZITEK
Duration: 2023-2025
Participants: BIOLAN HEALTH
Funding body: Gobierno Vasco
File no.: ZL-2023/00027
Development of a new POC device for the diagnosis of 25(OH)D deficiency
Acronym: D-OREKAPOC
Financing Program: HAZITEK
Duration: 2023
Participants: BIOLAN HEALTH
Funding body: Gobierno Vasco
File no.: ZL-2023/00929
Development of new diagnostic devices and immunomodulatory drugs based on 25(OH)D and VDR receptor agonists for the treatment of VitD deficiency and associated pathologies
Acronym: D-OREKA
Financing Program: HAZITEK
Duration: 2021-2027
Participants: BIOLAN HEALTH, FAES FARMA, ULMA Medical Technologies
Funding body: Gobierno Vasco
File no.: ZL-2022/00703 – D-OREKA
Design of optimised biosensing platforms for application in the development of Point of Care devices.
Acronym:
Financing Program: BIKAINTEK
Duration: 2019-2023
Participants: BIOLAN HEALTH
Funding body: Gobierno Vasco
Projects carried out
BIOLAN HEALTH is committed to collaborative projects as a way to increase its knowledge and technical skills.
OSASUNBERRI: Research and Acquisition of Scientific-Technological Infrastructure Project
Acronym: OSASUNBERRI
Duration: 2022
Participants: BIOLAN MICROBIOSENSORES S.L., BIOLAN HEALTH S.L., C4E CONSULTING SERVICES, S.L., DHEMEN DESIGN, S.L., FAES FARMA S.A., Galbaian S. Coop, GOGOA Mobility Robots S.L., Histocell S. L., INNOVATIVE TECHNOLOGIES IN BIOLOGICAL SYSTEMS S. L., Construcciones mecánicas Lazpiur S. L. U., Mikrobiomik Healthcare Company S.L., Mizar Health, Naru Intelligence Solutions S. L., P4Q Electronics S. L. U., LARRAÑAGA PLASTICOS S.A., Fundación Tecnalia Research & Innovation, Fundación Tekniker, Policlínica Gipuzkoa S.A., Inviza S.A., Casa Hermanas Hospitalarias Aita Menni, IQUIMESA SERVICIOS SANITARIOS S.L.U.
Funding body: Gobierno Vasco
Platform for rapid and reliable detection of viruses based on nanobodies and polymeric nanoparticles - HAZITEK
Acronym: P4V
Financing Program: HAZITEK
Duration: 2021-2022
Participants: Ikerlat, Innoprot, Biolan Health, Biolan
Funding body: Gobierno Vasco
File no.: ZL-2022/00072 – P4V
Platform for rapid and reliable detection of viruses based on nanobodies and polymeric nanoparticles - IDI
Acronym: P4V
Financing Program: IDI
Duration: 2021-2022
Participants: Ikerlat, Innoprot, Biolan Health, Biolan
Funding body: CDTI/Ministerio de Ciencia e Innovación
File no.: IDI-20211055
POCVIT: PoC device for the monitoring of vitamin D deficiency
Acronym: POCVIT
Financing Program: TORRES QUEVEDO
Duration: 2019-2022
Participants: BIOLAN HEALTH
Funding body: MICINN
OSAVIT: PoC device for the detection and monitoring of Vitamin D deficiency based on 25(OH)D quantification (2021)
Acronym: OSAVIT
Financing Program: HAZITEK
Duration: 2021
Participants: BIOLAN HEALTH, FAES
Funding body: Gobierno Vasco
File no.: ZL-2021/00366
OSAVIT: PoC device for the detection and monitoring of Vitamin D deficiency based on 25(OH)D quantification (2020)
Acronym: OSAVIT
Financing Program: HAZITEK
Duration: 2020
Participants: BIOLAN HEALTH, FAES
Funding body: Gobierno Vasco
File no.: ZL-2020/00951
OSAVIT: Point of Care Device for Vitamin D deficiency monitoring
Acronym: OSAVIT
Financing Program: H2020-INNOSUP
Duration: 2019
Participants: BIOLAN HEALTH
Funding body: European Commission
PoC devices based on microfluidic and biosensing technologies for in vitro diagnostics
Acronym: OSASEN
Financing Program: Programa NEOTEC
Duration: 2018-2019
Participants: OSASEN SENSORES
Funding body: CDTI- Centro para el Desarrollo Tecnológico Industrial
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